There are killers that go undetected. One is Hepatitis C. You can have Hep C for twenty years or more and have no symptoms except feeling tired. Up until the late 90s, there was no cure. Now there is a therapy for Hep C that is given over the course of a year, which cures it or puts it in remission.
There are many illnesses that take lives every day, so the best thing to do is to get a check up and take care of yourself.